Contents: Chapter 1. Introduction/Chapter 2. Role of Water and Effects of Small Ions in Site-specific Protein-DNA Interactions/Chapter 3. Structural Basis for Sequence-specific DNA Recognition by Transcription Factors and their Complexes/Chapter 4. Indirect Readout of DNA Sequence by Proteins/Chapter 5. Single-stranded Nucleic Acid (SSNA)-binding Proteins/Chapter 6. DNA Junctions and their Interaction with Resolving Enzymes/Chapter 7. RNA-protein Interactions in Ribonucleoprotein Particles and Ribonucleases/Chapter 8. Bending and Compaction of DNA by Proteins/Chapter 9. Mode of Action of Proteins with RNA Chaperone Activity/Chapter 10. Structure and Function of DNA Topoisomerases/Chapter 11. DNA Transposases/Chapter 12. Site-specific Recombinases/Chapter 13. DNA Nucleases/Chapter 14. RNA-mo- difying Enzymes